Treatment of Human Glioblastoma U251 Cells with Sulforaphane and a Peptide Nucleic Acid (PNA) Targeting miR-15b-5p: Synergistic Effects on Induction of Apoptosis

Glioblastoma multiforme (GBM) is a lethal malignant tumor accounting for 42% of the tumors of the central nervous system, the median survival being 15 months. At present, no curative treatment is available for GBM and new drugs and therapeutic protocols are urgently needed. In this context, combined...

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Detalles Bibliográficos
Autores principales: Gasparello, Jessica, Papi, Chiara, Zurlo, Matteo, Gambari, Laura, Rozzi, Andrea, Manicardi, Alex, Corradini, Roberto, Gambari, Roberto, Finotti, Alessia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875359/
https://www.ncbi.nlm.nih.gov/pubmed/35209084
http://dx.doi.org/10.3390/molecules27041299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875359/
https://www.ncbi.nlm.nih.gov/pubmed/35209084
http://dx.doi.org/10.3390/molecules27041299

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