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Preclinical PET Imaging of Granzyme B Shows Promotion of Immunological Response Following Combination Paclitaxel and Immune Checkpoint Inhibition in Triple Negative Breast Cancer

Advancements in monitoring and predicting of patient-specific response of triple negative breast cancer (TNBC) to immunotherapy (IMT) with and without chemotherapy are needed. Using granzyme B-specific positron emission tomography (GZP-PET) imaging, we aimed to monitor changes in effector cell activ...

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Detalles Bibliográficos
Autores principales: Napier, Tiara S., Hunter, Chanelle L., Song, Patrick N., Larimer, Benjamin M., Sorace, Anna G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875418/
https://www.ncbi.nlm.nih.gov/pubmed/35214172
http://dx.doi.org/10.3390/pharmaceutics14020440