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A Genetically Encoded Approach for Breaking Chromatin Symmetry

[Image: see text] Nucleosomes frequently exist as asymmetric species in native chromatin contexts. Current methods for the traceless generation of these heterotypic chromatin substrates are inefficient and/or difficult to implement. Here, we report an application of the SpyCatcher/SpyTag system as a...

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Detalles Bibliográficos
Autores principales: Lukasak, Bradley J., Thompson, Robert E., Mitchener, Michelle M., Feng, Vanessa J., Bagert, John D., Muir, Tom W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875426/
https://www.ncbi.nlm.nih.gov/pubmed/35233450
http://dx.doi.org/10.1021/acscentsci.1c01332