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Osteocrin, a bone-derived humoral factor, exerts a renoprotective role in ischemia–reperfusion injury in mice

BACKGROUND: Osteocrin (OSTN), a bone-derived humoral factor, was reported to act on heart and bone by potentiating the natriuretic peptide (NP) system. Ostn gene polymorphisms have been associated with renal function decline, but its pathophysiological role in the kidney remains unclear. METHODS: Th...

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Detalles Bibliográficos
Autores principales: Nishiguchi, Yoshihiko, Hata, Yusuke, Date, Ryosuke, Fujimoto, Daisuke, Umemoto, Shuro, Kanki, Tomoko, Yokoi, Hideki, Mori, Keita P, Handa, Takaya, Watanabe-Takano, Haruko, Kanai, Yugo, Yasoda, Akihiro, Izumi, Yuichiro, Kakizoe, Yutaka, Mochizuki, Naoki, Mukoyama, Masashi, Kuwabara, Takashige
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875462/
https://www.ncbi.nlm.nih.gov/pubmed/34610136
http://dx.doi.org/10.1093/ndt/gfab286