The Osteogenesis Imperfecta Type V Mutant BRIL/IFITM5 Promotes Transcriptional Activation of MEF2, NFATc, and NR4A in Osteoblasts

BRIL (bone restricted ifitm-like; also known as IFITM5) is a transmembrane protein expressed in osteoblasts. Although its role in skeletal development and homeostasis is unknown, mutations in BRIL result in rare dominant forms of osteogenesis imperfecta. The pathogenic mechanism has been proposed to...

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Detalles Bibliográficos
Autores principales: Maranda, Vincent, Gaumond, Marie-Hélène, Moffatt, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875491/
https://www.ncbi.nlm.nih.gov/pubmed/35216266
http://dx.doi.org/10.3390/ijms23042148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875491/
https://www.ncbi.nlm.nih.gov/pubmed/35216266
http://dx.doi.org/10.3390/ijms23042148

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