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In Vitro Inhibition of Replication of Dengue Virus Serotypes 1–4 by siRNAs Bound to Non-Toxic Liposomes

Dengue virus is a ssRNA+ flavivirus, which produces the dengue disease in humans. Currently, no specific treatment exists. siRNAs regulate gene expression and have been used systematically to silence viral genomes; however, they require controlled release. Liposomes show favorable results encapsulat...

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Detalles Bibliográficos
Autores principales: Rodriguez-Salazar, Carlos Andrés, Recalde-Reyes, Delia Piedad, Bedoya, Juan Pablo, Padilla-Sanabria, Leonardo, Castaño-Osorio, Jhon Carlos, Giraldo, Maria Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875542/
https://www.ncbi.nlm.nih.gov/pubmed/35215929
http://dx.doi.org/10.3390/v14020339