Development and Validation of Open-Source R Package HMCtdm for Therapeutic Drug Monitoring

Most therapeutic drug monitoring (TDM) packages are based on the maximum a posteriori (MAP) estimation. In this study, HMCtdm, a new TDM package, was developed using a Hamiltonian Monte Carlo (HMC) simulation. The estimation process of HMCtdm for the drugs amikacin, vancomycin, theophylline, and phe...

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Detalles Bibliográficos
Autores principales: Lee, Sooyoung, Song, Moonsik, Lim, Woojae, Song, Eunjung, Han, Jongdae, Kim, Bo-Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875672/
https://www.ncbi.nlm.nih.gov/pubmed/35215240
http://dx.doi.org/10.3390/ph15020127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875672/
https://www.ncbi.nlm.nih.gov/pubmed/35215240
http://dx.doi.org/10.3390/ph15020127

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