Pharmacological Inhibition of Spermine Oxidase Suppresses Excitotoxicity Induced Neuroinflammation in Mouse Retina

Polyamine oxidation plays a major role in neurodegenerative diseases. Previous studies from our laboratory demonstrated that spermine oxidase (SMOX, a member of the polyamine oxidase family) inhibition using MDL 72527 reduced neurodegeneration in models of retinal excitotoxicity and diabetic retinop...

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Detalles Bibliográficos
Autores principales: Alfarhan, Moaddey, Liu, Fang, Shan, Shengshuai, Pichavaram, Prahalathan, Somanath, Payaningal R., Narayanan, S. Priya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875684/
https://www.ncbi.nlm.nih.gov/pubmed/35216248
http://dx.doi.org/10.3390/ijms23042133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875684/
https://www.ncbi.nlm.nih.gov/pubmed/35216248
http://dx.doi.org/10.3390/ijms23042133

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