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Pharmacological Inhibition of Spermine Oxidase Suppresses Excitotoxicity Induced Neuroinflammation in Mouse Retina

Polyamine oxidation plays a major role in neurodegenerative diseases. Previous studies from our laboratory demonstrated that spermine oxidase (SMOX, a member of the polyamine oxidase family) inhibition using MDL 72527 reduced neurodegeneration in models of retinal excitotoxicity and diabetic retinop...

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Detalles Bibliográficos
Autores principales:	Alfarhan, Moaddey, Liu, Fang, Shan, Shengshuai, Pichavaram, Prahalathan, Somanath, Payaningal R., Narayanan, S. Priya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875684/ https://www.ncbi.nlm.nih.gov/pubmed/35216248 http://dx.doi.org/10.3390/ijms23042133

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