Oral Formulation Based on Irbesartan Nanocrystals Improve Drug Solubility, Absorbability, and Efficacy

We previously reported that the bioavailability (BA) of irbesartan (IRB), a BSC class II drug, was improved by preparing nanocrystalline suspensions. However, nanocrystalline suspensions have chemical and physical instabilities and must be converted into tablets through drying approaches in order to...

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Detalles Bibliográficos
Autores principales: Nagai, Noriaki, Ogata, Fumihiko, Ike, Ayari, Shimomae, Yurisa, Osako, Hanano, Nakazawa, Yosuke, Yamamoto, Naoki, Kawasaki, Naohito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875686/
https://www.ncbi.nlm.nih.gov/pubmed/35214118
http://dx.doi.org/10.3390/pharmaceutics14020387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875686/
https://www.ncbi.nlm.nih.gov/pubmed/35214118
http://dx.doi.org/10.3390/pharmaceutics14020387

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