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Oral Formulation Based on Irbesartan Nanocrystals Improve Drug Solubility, Absorbability, and Efficacy
We previously reported that the bioavailability (BA) of irbesartan (IRB), a BSC class II drug, was improved by preparing nanocrystalline suspensions. However, nanocrystalline suspensions have chemical and physical instabilities and must be converted into tablets through drying approaches in order to...
Autores principales: | Nagai, Noriaki, Ogata, Fumihiko, Ike, Ayari, Shimomae, Yurisa, Osako, Hanano, Nakazawa, Yosuke, Yamamoto, Naoki, Kawasaki, Naohito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875686/ https://www.ncbi.nlm.nih.gov/pubmed/35214118 http://dx.doi.org/10.3390/pharmaceutics14020387 |
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