Elevated Risk of Fluoropyrimidine-Associated Toxicity in European Patients with DPYD Genetic Polymorphism: A Systematic Review and Meta-Analysis

Background: Fluoropyrimidine is widely used owing to its clinical efficacy, however, patients with dihydropyrimidine dehydrogenase (DPD) deficiency can experience fluoropyrimidine-associated toxicity. The dihydropyrimidine dehydrogenase (DPYD) gene encodes DPD, and studies suggest that DPYD polymorp...

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Detalles Bibliográficos
Autores principales: Kim, Woorim, Cho, Young-Ah, Kim, Dong-Chul, Lee, Kyung-Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875904/
https://www.ncbi.nlm.nih.gov/pubmed/35207713
http://dx.doi.org/10.3390/jpm12020225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875904/
https://www.ncbi.nlm.nih.gov/pubmed/35207713
http://dx.doi.org/10.3390/jpm12020225

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