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Elevated Risk of Fluoropyrimidine-Associated Toxicity in European Patients with DPYD Genetic Polymorphism: A Systematic Review and Meta-Analysis

Background: Fluoropyrimidine is widely used owing to its clinical efficacy, however, patients with dihydropyrimidine dehydrogenase (DPD) deficiency can experience fluoropyrimidine-associated toxicity. The dihydropyrimidine dehydrogenase (DPYD) gene encodes DPD, and studies suggest that DPYD polymorp...

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Detalles Bibliográficos
Autores principales:	Kim, Woorim, Cho, Young-Ah, Kim, Dong-Chul, Lee, Kyung-Eun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875904/ https://www.ncbi.nlm.nih.gov/pubmed/35207713 http://dx.doi.org/10.3390/jpm12020225

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