Implementing Pre-Therapeutic UGT1A1 Genotyping in Clinical Practice: A Real-Life Study

Current guidelines recommend pre-therapeutic UGT1A1 genotyping to guide irinotecan dosing, but the usefulness of this approach remains to be clarified. In 247 patients with advanced gastrointestinal cancers undergoing irinotecan-based chemotherapy, we prospectively performed UGT1A1*28 genotyping and...

Descripción completa

Detalles Bibliográficos
Autores principales: Personeni, Nicola, Giordano, Laura, Michelini, Angelica, D’Alessio, Antonio, Cammarota, Antonella, Bozzarelli, Silvia, Pressiani, Tiziana, Prete, Maria Giuseppina, Sandri, Maria Teresa, Stioui, Sabine, Germagnoli, Luca, Santoro, Armando, Rimassa, Lorenza, Mineri, Rossana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875990/
https://www.ncbi.nlm.nih.gov/pubmed/35207692
http://dx.doi.org/10.3390/jpm12020204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875990/
https://www.ncbi.nlm.nih.gov/pubmed/35207692
http://dx.doi.org/10.3390/jpm12020204

Ejemplares similares