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Dual-Drug Delivery via Zein In Situ Forming Implants Augmented with Titanium-Doped Bioactive Glass for Bone Regeneration: Preparation, In Vitro Characterization, and In Vivo Evaluation

In situ forming implants (IFIs) are non-surgical approach using biodegradable polymers to treat bone fractures. The study aimed at preparing dual-drug-loaded IFIs to deliver pitavastatin (osteogenic drug) and tedizolid (antibiotic) using zein as the implant matrix via solvent-induced phase inversion...

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Detalles Bibliográficos
Autores principales: Eldeeb, Alaa Emad, Salah, Salwa, Mabrouk, Mostafa, Amer, Mohammed S., Elkasabgy, Nermeen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876030/
https://www.ncbi.nlm.nih.gov/pubmed/35214007
http://dx.doi.org/10.3390/pharmaceutics14020274