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Rational Development of a Carrier-Free Dry Powder Inhalation Formulation for Respiratory Viral Infections via Quality by Design: A Drug-Drug Cocrystal of Favipiravir and Theophylline

Formulating pharmaceutical cocrystals as inhalable dosage forms represents a unique niche in effective management of respiratory infections. Favipiravir, a broad-spectrum antiviral drug with potential pharmacological activity against SARS-CoV-2, exhibits a low aqueous solubility. An ultra-high oral...

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Detalles Bibliográficos
Autores principales: Wong, Si Nga, Weng, Jingwen, Ip, Ignatius, Chen, Ruipeng, Lakerveld, Richard, Telford, Richard, Blagden, Nicholas, Scowen, Ian J., Chow, Shing Fung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876093/
https://www.ncbi.nlm.nih.gov/pubmed/35214034
http://dx.doi.org/10.3390/pharmaceutics14020300