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Rational Development of a Carrier-Free Dry Powder Inhalation Formulation for Respiratory Viral Infections via Quality by Design: A Drug-Drug Cocrystal of Favipiravir and Theophylline
Formulating pharmaceutical cocrystals as inhalable dosage forms represents a unique niche in effective management of respiratory infections. Favipiravir, a broad-spectrum antiviral drug with potential pharmacological activity against SARS-CoV-2, exhibits a low aqueous solubility. An ultra-high oral...
Autores principales: | Wong, Si Nga, Weng, Jingwen, Ip, Ignatius, Chen, Ruipeng, Lakerveld, Richard, Telford, Richard, Blagden, Nicholas, Scowen, Ian J., Chow, Shing Fung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876093/ https://www.ncbi.nlm.nih.gov/pubmed/35214034 http://dx.doi.org/10.3390/pharmaceutics14020300 |
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