Identifying Inhibitors of −1 Programmed Ribosomal Frameshifting in a Broad Spectrum of Coronaviruses

Recurrent outbreaks of novel zoonotic coronavirus (CoV) diseases in recent years have highlighted the importance of developing therapeutics with broad-spectrum activity against CoVs. Because all CoVs use −1 programmed ribosomal frameshifting (−1 PRF) to control expression of key viral proteins, the...

Descripción completa

Detalles Bibliográficos
Autores principales: Munshi, Sneha, Neupane, Krishna, Ileperuma, Sandaru M., Halma, Matthew T. J., Kelly, Jamie A., Halpern, Clarissa F., Dinman, Jonathan D., Loerch, Sarah, Woodside, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876150/
https://www.ncbi.nlm.nih.gov/pubmed/35215770
http://dx.doi.org/10.3390/v14020177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876150/
https://www.ncbi.nlm.nih.gov/pubmed/35215770
http://dx.doi.org/10.3390/v14020177

Ejemplares similares