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Identifying Inhibitors of −1 Programmed Ribosomal Frameshifting in a Broad Spectrum of Coronaviruses

Recurrent outbreaks of novel zoonotic coronavirus (CoV) diseases in recent years have highlighted the importance of developing therapeutics with broad-spectrum activity against CoVs. Because all CoVs use −1 programmed ribosomal frameshifting (−1 PRF) to control expression of key viral proteins, the...

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Detalles Bibliográficos
Autores principales:	Munshi, Sneha, Neupane, Krishna, Ileperuma, Sandaru M., Halma, Matthew T. J., Kelly, Jamie A., Halpern, Clarissa F., Dinman, Jonathan D., Loerch, Sarah, Woodside, Michael T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876150/ https://www.ncbi.nlm.nih.gov/pubmed/35215770 http://dx.doi.org/10.3390/v14020177

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