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Searching for Low Probability Opening Events in a DNA Sliding Clamp
The [Formula: see text] subunit of E. coli DNA polymererase III is a DNA sliding clamp associated with increasing the processivity of DNA synthesis. In its free form, it is a circular homodimer structure that can accomodate double-stranded DNA in a nonspecific manner. An open state of the clamp must...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876151/ https://www.ncbi.nlm.nih.gov/pubmed/35207548 http://dx.doi.org/10.3390/life12020261 |