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Searching for Low Probability Opening Events in a DNA Sliding Clamp

The [Formula: see text] subunit of E. coli DNA polymererase III is a DNA sliding clamp associated with increasing the processivity of DNA synthesis. In its free form, it is a circular homodimer structure that can accomodate double-stranded DNA in a nonspecific manner. An open state of the clamp must...

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Detalles Bibliográficos
Autores principales: Esmaeeli, Reza, Andal, Benedict, Perez, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876151/
https://www.ncbi.nlm.nih.gov/pubmed/35207548
http://dx.doi.org/10.3390/life12020261