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Oxidation of Drugs during Drug Product Development: Problems and Solutions

Oxidation is the second most common degradation pathway for pharmaceuticals, after hydrolysis. However, in contrast to hydrolysis, oxidation is mechanistically more complex and produces a wider range of degradation products; oxidation is thus harder to control. The propensity of a drug towards oxida...

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Detalles Bibliográficos
Autores principales: Gabrič, Alen, Hodnik, Žiga, Pajk, Stane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876153/
https://www.ncbi.nlm.nih.gov/pubmed/35214057
http://dx.doi.org/10.3390/pharmaceutics14020325