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Oxidation of Drugs during Drug Product Development: Problems and Solutions
Oxidation is the second most common degradation pathway for pharmaceuticals, after hydrolysis. However, in contrast to hydrolysis, oxidation is mechanistically more complex and produces a wider range of degradation products; oxidation is thus harder to control. The propensity of a drug towards oxida...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876153/ https://www.ncbi.nlm.nih.gov/pubmed/35214057 http://dx.doi.org/10.3390/pharmaceutics14020325 |