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Effective Synthesis and Antifouling Activity of Dolastatin 16 Derivatives

Some derivatives of dolastatin 16, a depsipeptide natural product first obtained from the sea hare Dolabella auricularia, were synthesized through second-generation synthesis of two unusual amino acids, dolaphenvaline and dolamethylleuine. The second-generation synthesis enabled derivatizations such...

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Detalles Bibliográficos
Autores principales: Casalme, Loida O., Katayama, Keisuke, Hayakawa, Yoshiki, Nakamura, Kensuke, Yamauchi, Arisa, Nogata, Yasuyuki, Yoshimura, Erina, Matsuda, Fuyuhiko, Umezawa, Taiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876244/
https://www.ncbi.nlm.nih.gov/pubmed/35200652
http://dx.doi.org/10.3390/md20020124