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Serum Thioredoxin-80 is associated with age, ApoE4, and neuropathological biomarkers in Alzheimer’s disease: a potential early sign of AD

BACKGROUND: Thioredoxin-80 (Trx80) is a cleavage product from the redox-active protein Thioredoxin-1 and has been previously described as a pro-inflammatory cytokine secreted by immune cells. Previous studies in our group reported that Trx80 levels are depleted in Alzheimer’s disease (AD) brains. Ho...

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Detalles Bibliográficos
Autores principales: Goikolea, Julen, Gerenu, Gorka, Daniilidou, Makrina, Mangialasche, Francesca, Mecocci, Patrizia, Ngandu, Tiia, Rinne, Juha, Solomon, Alina, Kivipelto, Miia, Cedazo-Minguez, Angel, Sandebring-Matton, Anna, Maioli, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876266/
https://www.ncbi.nlm.nih.gov/pubmed/35209952
http://dx.doi.org/10.1186/s13195-022-00979-9