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Serum Thioredoxin-80 is associated with age, ApoE4, and neuropathological biomarkers in Alzheimer’s disease: a potential early sign of AD
BACKGROUND: Thioredoxin-80 (Trx80) is a cleavage product from the redox-active protein Thioredoxin-1 and has been previously described as a pro-inflammatory cytokine secreted by immune cells. Previous studies in our group reported that Trx80 levels are depleted in Alzheimer’s disease (AD) brains. Ho...
Autores principales: | Goikolea, Julen, Gerenu, Gorka, Daniilidou, Makrina, Mangialasche, Francesca, Mecocci, Patrizia, Ngandu, Tiia, Rinne, Juha, Solomon, Alina, Kivipelto, Miia, Cedazo-Minguez, Angel, Sandebring-Matton, Anna, Maioli, Silvia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876266/ https://www.ncbi.nlm.nih.gov/pubmed/35209952 http://dx.doi.org/10.1186/s13195-022-00979-9 |
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