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Quantitative Visualization of the Interaction between Complement Component C1 and Immunoglobulin G: The Effect of C(H)1 Domain Deletion
Immunoglobulin G (IgG) adopts a modular multidomain structure that mediates antigen recognition and effector functions, such as complement-dependent cytotoxicity. IgG molecules are self-assembled into a hexameric ring on antigen-containing membranes, recruiting the complement component C1q. In order...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876274/ https://www.ncbi.nlm.nih.gov/pubmed/35216207 http://dx.doi.org/10.3390/ijms23042090 |