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Quantitative Visualization of the Interaction between Complement Component C1 and Immunoglobulin G: The Effect of C(H)1 Domain Deletion

Immunoglobulin G (IgG) adopts a modular multidomain structure that mediates antigen recognition and effector functions, such as complement-dependent cytotoxicity. IgG molecules are self-assembled into a hexameric ring on antigen-containing membranes, recruiting the complement component C1q. In order...

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Detalles Bibliográficos
Autores principales:	Yanaka, Saeko, Nishiguchi, Shigetaka, Yogo, Rina, Watanabe, Hiroki, Shen, Jiana, Yagi, Hirokazu, Uchihashi, Takayuki, Kato, Koichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876274/ https://www.ncbi.nlm.nih.gov/pubmed/35216207 http://dx.doi.org/10.3390/ijms23042090

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