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Epigenetic Modulation of Gremlin-1/NOTCH Pathway in Experimental Crescentic Immune-Mediated Glomerulonephritis

Crescentic glomerulonephritis is a devastating autoimmune disease that without early and properly treatment may rapidly progress to end-stage renal disease and death. Current immunosuppressive treatment provides limited efficacy and an important burden of adverse events. Epigenetic drugs are a sourc...

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Detalles Bibliográficos
Autores principales: Tejedor-Santamaria, Lucia, Morgado-Pascual, Jose Luis, Marquez-Exposito, Laura, Suarez-Alvarez, Beatriz, Rodrigues-Diez, Raul R., Tejera-Muñoz, Antonio, Marchant, Vanessa, Mezzano, Sergio, Lopez-Larrea, Carlos, Sola, Anna, Fernandez-Juarez, Gema Maria, Ortiz, Alberto, Rayego-Mateos, Sandra, Ruiz-Ortega, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876310/
https://www.ncbi.nlm.nih.gov/pubmed/35215234
http://dx.doi.org/10.3390/ph15020121