Cargando…

Proline Dehydrogenase/Proline Oxidase (PRODH/POX) Is Involved in the Mechanism of Metformin-Induced Apoptosis in C32 Melanoma Cell Line

The role of proline dehydrogenase/proline oxidase (PRODH/POX) in the mechanism of antineoplastic activity of metformin (MET) was studied in C32 melanoma cells. PRODH/POX is a mitochondrial enzyme-degrading proline that is implicated in the regulation of cancer cell survival/apoptosis. The enzyme is...

Descripción completa

Detalles Bibliográficos
Autores principales: Oscilowska, Ilona, Rolkowski, Karol, Baszanowska, Weronika, Huynh, Thi Yen Ly, Lewoniewska, Sylwia, Nizioł, Magdalena, Sawicka, Magdalena, Bielawska, Katarzyna, Szoka, Paweł, Miltyk, Wojciech, Palka, Jerzy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876342/
https://www.ncbi.nlm.nih.gov/pubmed/35216470
http://dx.doi.org/10.3390/ijms23042354