Hepatic Fis1 regulates mitochondrial integrated stress response and improves metabolic homeostasis

Mitophagy and mitochondrial integrated stress response (ISR) are 2 primary protective mechanisms to maintain functional mitochondria. Whether these 2 processes are coordinately regulated remains unclear. Here we show that mitochondrial fission 1 protein (Fis1), which is required for completion of mi...

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Detalles Bibliográficos
Autores principales: Liou, Yae-Huei, Personnaz, Jean, Jacobi, David, Knudsen, Nelson H., Chalom, Mayer M., Starost, Kyle A., Nnah, Israel C., Lee, Chih-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876406/
https://www.ncbi.nlm.nih.gov/pubmed/35015731
http://dx.doi.org/10.1172/jci.insight.150041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876406/
https://www.ncbi.nlm.nih.gov/pubmed/35015731
http://dx.doi.org/10.1172/jci.insight.150041

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