Cargando…

MICU1-dependent mitochondrial calcium uptake regulates lung alveolar type 2 cell plasticity and lung regeneration

Lung alveolar type 2 (AT2) cells are progenitors for alveolar type 1 (AT1) cells. Although many factors regulate AT2 cell plasticity, the role of mitochondrial calcium ((m)Ca(2+)) uptake in controlling AT2 cells remains unclear. We previously identified that the miR-302 family supports lung epitheli...

Descripción completa

Detalles Bibliográficos
Autores principales: Ali, Mir, Zhang, Xiaoying, LaCanna, Ryan, Tomar, Dhanendra, Elrod, John W., Tian, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876408/
https://www.ncbi.nlm.nih.gov/pubmed/35050901
http://dx.doi.org/10.1172/jci.insight.154447