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ChREBPβ is dispensable for the control of glucose homeostasis and energy balance

Impaired glucose metabolism is observed in obesity and type 2 diabetes. Glucose controls gene expression through the transcription factor ChREBP in liver and adipose tissues. Mlxipl encodes 2 isoforms: ChREBPα, the full-length form (translocation into the nucleus is under the control of glucose), an...

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Detalles Bibliográficos
Autores principales: Recazens, Emeline, Tavernier, Geneviève, Dufau, Jérémy, Bergoglio, Camille, Benhamed, Fadila, Cassant-Sourdy, Stéphanie, Marques, Marie-Adeline, Caspar-Bauguil, Sylvie, Brion, Alice, Monbrun, Laurent, Dentin, Renaud, Ferrier, Clara, Leroux, Mélanie, Denechaud, Pierre-Damien, Moro, Cedric, Concordet, Jean-Paul, Postic, Catherine, Mouisel, Etienne, Langin, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876429/
https://www.ncbi.nlm.nih.gov/pubmed/35041621
http://dx.doi.org/10.1172/jci.insight.153431