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A neutrophil/TGF-β axis limits the pathogenicity of allergen-specific CD4(+) T cells

The intensity and longevity of inflammatory responses to inhaled allergens is determined largely by the balance between effector and regulatory immune responses, but the mechanisms that determine the relative magnitudes of these opposing forces remain poorly understood. We have found that the type o...

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Detalles Bibliográficos
Autores principales: Whitehead, Gregory S., Thomas, Seddon Y., Nakano, Keiko, Royer, Derek J., Burke, Catherine G., Nakano, Hideki, Cook, Donald N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876454/
https://www.ncbi.nlm.nih.gov/pubmed/35191395
http://dx.doi.org/10.1172/jci.insight.150251