Angiogenesis depends upon EPHB4-mediated export of collagen IV from vascular endothelial cells

Capillary malformation-arteriovenous malformation (CM-AVM) is a blood vascular anomaly caused by inherited loss-of-function mutations in RASA1 or EPHB4 genes, which encode p120 Ras GTPase-activating protein (p120 RasGAP/RASA1) and Ephrin receptor B4 (EPHB4). However, whether RASA1 and EPHB4 function...

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Detalles Bibliográficos
Autores principales: Chen, Di, Hughes, Elizabeth D., Saunders, Thomas L., Wu, Jiangping, Vasquez, Magda N. Hernandez, Makinen, Taija, King, Philip D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876457/
https://www.ncbi.nlm.nih.gov/pubmed/35015735
http://dx.doi.org/10.1172/jci.insight.156928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876457/
https://www.ncbi.nlm.nih.gov/pubmed/35015735
http://dx.doi.org/10.1172/jci.insight.156928

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