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Angiogenesis depends upon EPHB4-mediated export of collagen IV from vascular endothelial cells

Capillary malformation-arteriovenous malformation (CM-AVM) is a blood vascular anomaly caused by inherited loss-of-function mutations in RASA1 or EPHB4 genes, which encode p120 Ras GTPase-activating protein (p120 RasGAP/RASA1) and Ephrin receptor B4 (EPHB4). However, whether RASA1 and EPHB4 function...

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Detalles Bibliográficos
Autores principales:	Chen, Di, Hughes, Elizabeth D., Saunders, Thomas L., Wu, Jiangping, Vasquez, Magda N. Hernandez, Makinen, Taija, King, Philip D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876457/ https://www.ncbi.nlm.nih.gov/pubmed/35015735 http://dx.doi.org/10.1172/jci.insight.156928

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