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Islet transplantation into brown adipose tissue can delay immune rejection

Type 1 diabetes is an autoimmune disease characterized by insulin-producing β cell destruction. Although islet transplantation restores euglycemia and improves patient outcomes, an ideal transplant site remains elusive. Brown adipose tissue (BAT) has a highly vascularized and antiinflammatory microe...

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Detalles Bibliográficos
Autores principales: Kepple, Jessica D., Barra, Jessie M., Young, Martin E., Hunter, Chad S., Tse, Hubert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876467/
https://www.ncbi.nlm.nih.gov/pubmed/35015736
http://dx.doi.org/10.1172/jci.insight.152800