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Prdm6 controls heart development by regulating neural crest cell differentiation and migration

The molecular mechanisms that drive the acquisition of distinct neural crest cell (NCC) fates is still poorly understood. Here, we identified Prdm6 as an epigenetic modifier that temporally and spatially regulates the expression of NCC specifiers and determines the fate of a subset of migrating card...

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Detalles Bibliográficos
Autores principales: Hong, Lingjuan, Li, Na, Gasque, Victor, Mehta, Sameet, Ye, Lupeng, Wu, Yinyu, Li, Jinyu, Gewies, Andreas, Ruland, Jürgen, Hirschi, Karen K., Eichmann, Anne, Hendry, Caroline, van Dijk, David, Mani, Arya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876496/
https://www.ncbi.nlm.nih.gov/pubmed/35108221
http://dx.doi.org/10.1172/jci.insight.156046