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Prdm6 controls heart development by regulating neural crest cell differentiation and migration
The molecular mechanisms that drive the acquisition of distinct neural crest cell (NCC) fates is still poorly understood. Here, we identified Prdm6 as an epigenetic modifier that temporally and spatially regulates the expression of NCC specifiers and determines the fate of a subset of migrating card...
Autores principales: | Hong, Lingjuan, Li, Na, Gasque, Victor, Mehta, Sameet, Ye, Lupeng, Wu, Yinyu, Li, Jinyu, Gewies, Andreas, Ruland, Jürgen, Hirschi, Karen K., Eichmann, Anne, Hendry, Caroline, van Dijk, David, Mani, Arya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876496/ https://www.ncbi.nlm.nih.gov/pubmed/35108221 http://dx.doi.org/10.1172/jci.insight.156046 |
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