Structure-Based Discovery of N-Sulfonylpiperidine-3-Carboxamides as Novel Capsid Assembly Modulators for Potent Inhibition of HBV Replication

As a key element during HBV replication, a nucleocapsid is considered a promising target for the treatment of chronic hepatitis B. The present study aimed to identify small molecules as novel capsid assembly modulators with antiviral activity. Structure-based virtual screening of an integrated compo...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Yan, Yu, Yin, Jiaxin, Hu, Jie, Cai, Xuefei, Hu, Jieli, Xia, Jie, Wang, Kai, Tang, Ni, Huang, Luyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876525/
https://www.ncbi.nlm.nih.gov/pubmed/35215939
http://dx.doi.org/10.3390/v14020348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876525/
https://www.ncbi.nlm.nih.gov/pubmed/35215939
http://dx.doi.org/10.3390/v14020348

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