Physicochemical Characterizations and Pharmacokinetic Evaluation of Pentazocine Solid Lipid Nanoparticles against Inflammatory Pain Model

Pentazocine (PTZ), a narcotic-antagonist analgesic, has been extensively used in the treatment of initial carcinogenic or postoperative pain. Hepatic first-pass metabolism results in low oral bioavailability and high dose wastage. Herein, 10 mg (-)-Pentazocine (HPLC-grade) was incorporated to solid...

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Detalles Bibliográficos
Autores principales: Khan, Zaheer Ullah, Razzaq, Anam, Khan, Ahsan, Rehman, Naeem Ur, Khan, Hira, Khan, Taous, Khan, Ashraf Ullah, Althobaiti, Norah A., Menaa, Farid, Iqbal, Haroon, Khan, Naveed Ullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876599/
https://www.ncbi.nlm.nih.gov/pubmed/35214141
http://dx.doi.org/10.3390/pharmaceutics14020409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876599/
https://www.ncbi.nlm.nih.gov/pubmed/35214141
http://dx.doi.org/10.3390/pharmaceutics14020409

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