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Analysis of the Neutralizing Activity of Antibodies Targeting Open or Closed SARS-CoV-2 Spike Protein Conformations

SARS-CoV-2 infection elicits a polyclonal neutralizing antibody (nAb) response that primarily targets the spike protein, but it is still unclear which nAbs are immunodominant and what distinguishes them from subdominant nAbs. This information would however be crucial to predict the evolutionary traj...

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Detalles Bibliográficos
Autores principales: Cia, Gabriel, Pucci, Fabrizio, Rooman, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876721/
https://www.ncbi.nlm.nih.gov/pubmed/35216194
http://dx.doi.org/10.3390/ijms23042078