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High-Affinity Ratiometric Fluorescence Probe Based on 6-Amino-2,2′-Bipyridine Scaffold for Endogenous Zn(2+) and Its Application to Living Cells

Zinc is an essential trace element involved in many biological activities; however, its functions are not fully understood. To elucidate the role of endogenous labile Zn(2+), we developed a novel ratiometric fluorescence probe, 5-(4-methoxyphenyl)-4-(methylsulfanyl)-[2,2′-bipyridin]-6-amine (6 (rBpy...

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Detalles Bibliográficos
Autores principales: Hagimori, Masayori, Hara, Fumiko, Mizuyama, Naoko, Fujino, Takeshi, Saji, Hideo, Mukai, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876810/
https://www.ncbi.nlm.nih.gov/pubmed/35209077
http://dx.doi.org/10.3390/molecules27041287