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Oligonucleotide Therapeutics: From Discovery and Development to Patentability
Following the first proof of concept of using small nucleic acids to modulate gene expression, a long period of maturation led, at the end of the last century, to the first marketing authorization of an oligonucleotide-based therapy. Since then, 12 more compounds have hit the market and many more ar...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876811/ https://www.ncbi.nlm.nih.gov/pubmed/35213992 http://dx.doi.org/10.3390/pharmaceutics14020260 |