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AsKC11, a Kunitz Peptide from Anemonia sulcata, Is a Novel Activator of G Protein-Coupled Inward-Rectifier Potassium Channels

(1) Background: G protein-coupled inward-rectifier potassium (GIRK) channels, especially neuronal GIRK1/2 channels, have been the focus of intense research interest for developing drugs against brain diseases. In this context, venom peptides that selectively activate GIRK channels can be seen as a n...

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Detalles Bibliográficos
Autores principales: An, Dongchen, Pinheiro-Junior, Ernesto Lopes, Béress, László, Gladkikh, Irina, Leychenko, Elena, Undheim, Eivind A. B., Peigneur, Steve, Tytgat, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876855/
https://www.ncbi.nlm.nih.gov/pubmed/35200669
http://dx.doi.org/10.3390/md20020140