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Comparative Evaluation of Radiochemical and Biological Properties of (131)I- and [(99m)Tc]Tc(CO)(3)-Labeled RGD Analogues Planned to Interact with the α(v)β(3) Integrin Expressed in Glioblastoma

Radiolabeled peptides with high specificity for overexpressed receptors in tumor cells hold great promise for diagnostic and therapeutic applications. In this work, we aimed at comparing the radiolabeling efficiency and biological properties of two different RGD analogs: GRGDYV and GRGDHV, labeled w...

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Detalles Bibliográficos
Autores principales: Sobral, Danielle V., Fuscaldi, Leonardo L., Durante, Ana Claudia R., Mendonça, Fernanda F., de Oliveira, Larissa R., Miranda, Ana Cláudia C., Mejia, Jorge, Montor, Wagner R., de Barboza, Marycel F., Malavolta, Luciana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876959/
https://www.ncbi.nlm.nih.gov/pubmed/35215229
http://dx.doi.org/10.3390/ph15020116