Synthesis and Structure–Activity Relationship Studies of Benzimidazole-4,7-dione-Based P2X3 Receptor Antagonists as Novel Anti-Nociceptive Agents

P2X3 receptors (P2X3R) are ATP-gated ion channels predominantly expressed in C- and Aδ-fiber primary afferent neurons and have been introduced as a novel therapeutic target for neurological disorders, including neuropathic pain and chronic cough. Because of its localized distribution, antagonism of...

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Detalles Bibliográficos
Autores principales: Bae, Jinsu, Kim, Yeo-Ok, Han, Xuehao, Yoon, Myung-Ha, Kim, Woong-Mo, Kim, Yong-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877008/
https://www.ncbi.nlm.nih.gov/pubmed/35209126
http://dx.doi.org/10.3390/molecules27041337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877008/
https://www.ncbi.nlm.nih.gov/pubmed/35209126
http://dx.doi.org/10.3390/molecules27041337

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