Mitochondrial ROS-Mediated Metabolic and Cytotoxic Effects of Isoproterenol on Cardiomyocytes Are p53-Dependent and Reversed by Curcumin

Acute β-adrenergic stimulation contributes to heart failure. Here, we investigated the role of p53 in isoproterenol (ISO)-mediated metabolic and oxidative stress effects on cardiomyocytes and explored the direct protective effects offered by the antioxidant nutraceutical curcumin. Differentiated H9C...

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Detalles Bibliográficos
Autores principales: Lee, Jin Hee, Kim, Da Hae, Kim, MinA, Jung, Kyung-Ho, Lee, Kyung-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877017/
https://www.ncbi.nlm.nih.gov/pubmed/35209134
http://dx.doi.org/10.3390/molecules27041346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877017/
https://www.ncbi.nlm.nih.gov/pubmed/35209134
http://dx.doi.org/10.3390/molecules27041346

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