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DUX: One Transcription Factor Controls 2-Cell-like Fate

The double homeobox (Dux) gene, encoding a double homeobox transcription factor, is one of the key drivers of totipotency in mice. Recent studies showed Dux was temporally expressed at the 2-cell stage and acted as a transcriptional activator during zygotic genome activation (ZGA) in embryos. A simi...

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Detalles Bibliográficos
Autores principales: Ren, Wei, Gao, Leilei, Mou, Yaling, Deng, Wen, Hua, Jinlian, Yang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877164/
https://www.ncbi.nlm.nih.gov/pubmed/35216182
http://dx.doi.org/10.3390/ijms23042067