Cargando…

Pitfall in the Design and Analysis of Comparative Oncology Trials With a Time-to-Event Endpoint and Recommendations

When designing a comparative oncology trial for an overall or progression-free survival endpoint, investigators often quantify the treatment effect using a difference in median survival times. However, rather than directly designing the study to estimate this difference, it is almost always converte...

Descripción completa

Detalles Bibliográficos
Autores principales: McCaw, Zachary R, Kim, Dae Hyun, Wei, Lee-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877166/
https://www.ncbi.nlm.nih.gov/pubmed/35699499
http://dx.doi.org/10.1093/jncics/pkac007