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Changing Population Size in McDonald–Kreitman Style Analyses: Artifactual Correlations and Adaptive Evolution between Humans and Chimpanzees
It is known that methods to estimate the rate of adaptive evolution, which are based on the McDonald–Kreitman test, can be biased by changes in effective population size. Here, we demonstrate theoretically that changes in population size can also generate an artifactual correlation between the rate...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877167/ https://www.ncbi.nlm.nih.gov/pubmed/35143656 http://dx.doi.org/10.1093/gbe/evac022 |